数字农科院2.0

A Critical Review Of Antibiotic Resistance In Probiotic Bacteria

文献类型： 外文期刊

作者： Li, T; Teng, D; Mao, RY; Hao, Y; Wang, XM; Wang, JH

作者机构：

关键词： Probiotics; Intrinsic Antibiotic Resistance; Acquired Antibiotic Resistance; Mechanism; Potential Risks; Strategy

期刊名称： FOOD RESEARCH INTERNATIONAL

ISSN： 0963-9969

年卷期： 2020 年 136 卷

页码：

收录情况： JCR（2021版） ; EI（2021版）

摘要： Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit upon the host. At present, probiotics are gaining popularity worldwide and are widely used in food and medicine. Consumption of probiotics is increasing with further in-depth research on the relationship between intestinal flora and host health. Most people pay more attention to the function of probiotics but ignore their potential risks, such as infection and antibiotic resistance transfer to pathogenic microbes. Physiological functions, effects and mechanisms of action of probiotics were covered in this review, as well as the antibiotic resistance phenotypes, mechanisms and genes found in probiotics. Typical cases of antibiotic resistance of probiotics were also highlighted, as well as the potential risks (including pathogenicity, infectivity and excessive immune response) and corresponding strategies (dosage, formulation, and administration route). This timely study provides an avenue for further research, development and application of probiotics.

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