Identification and Predictions Regarding the Biosynthesis Pathway of Polyene Macrolides Produced by Streptomyces roseoflavus Men-myco-93-63
文献类型: 外文期刊
作者: Han Xing;Wang Jiao;Liu Lianna;Shen Fengying;Meng Qingfang;Li Xing;Li Yaning;Liua Daqun
作者机构:
关键词: antibiotic; antifungal activity; biosynthetic gene cluster; polyene macrolide; Streptomyces roseoflavus Men-myco-93-63
期刊名称: Applied and Environmental Microbiology
ISSN: 0099-2240
年卷期: 2021 年 87 卷 10 期
页码:
收录情况: JCR(2021版) ; EI(2021版)
摘要: A group of polyene macrolides mainly composed of two constituentswas isolated from the fermentation broth of Streptomyces roseoflavus Men-myco-93-63, which was isolated from soil where potato scabs were repressed naturally. Oneof these macrolides was roflamycoin, which was first reported in 1968, and the otherwas a novel compound named Men-myco-A, which had one methylene unit morethan roflamycoin. Together, they were designated RM. This group of antibiotics exhibitedbroad-spectrum antifungal activities in vitro against 17 plant-pathogenic fungi, with50% effective concentrations (EC50) of 2.05 to 7.09mg/ml and 90% effective concentrations(EC90) of 4.32 to 54.45mg/ml, which indicates their potential use in plant diseasecontrol. Furthermore, their biosynthetic gene cluster was identified, and the associatedbiosynthetic assembly line was proposed based on a module and domain analysis ofpolyketide synthases (PKSs), supported by findings from gene inactivation experiments. © 2021, American Society for Microbiology. All Rights Reserved.
分类号:
- 相关文献
作者其他论文 更多>>
-
Precise classification and regional delineation of maturity groups in soybean cultivars across China
作者:Wenwen Song;Luping Liu;Shi Sun;Tingting Wu;Haiyan Zeng;Shiyan Tian;Bincheng Sun;Wenbin Li;Lijun Liu;Shuming Wang;Han Xing;Xin'an Zhou;Hai Nian;Wencheng Lu;Xiaozeng Han;Shouyi Wang;Weiyuan Chen;Tai Guo;Xiqing Song;Zhongyan Tian;Yanxi Cheng;Shuhong Song;Lianshun Fu;Huicai Wang;Ruiping Luo;Xueyi Liu;Qi Liu;Guohong Zhang;Sihui Lu;Ran Xu;Suzhen Li;Weiguo Lu;Qi Zhang;Zongbiao Wang;Chengong Jiang;Weiliang Shen;Mingrong Zhang;Danhua Zhu;Ruizhen Wang;Yuan Chen;Tiejun Wang;Xingtao Zhu;Yong Zhan;Bingjun Jiang;Cailong Xu;Shan Yuan;Wensheng Hou;Junyi Gai;Cunxiang Wu;Tianfu Han
关键词:Maturity group;Optimum adaptation zone;Precise classification;Soybean
-
Preparative separation and purification of loliolide and epiloliolide from: Ascophyllum nodosum using amine-based microporous organic polymer for solid phase extraction coupled with macroporous resin and prep-HPLC
作者:Chi Hao;Qi Xia;Wang Xiaohui;Wang Ying;Han Xihong;Wang Jiao;Wang Hongwei
关键词:
-
Genome-wide association studies of plant architecture-related traits and 100-seed weight in soybean landraces
作者:Xiaoli Zhang;Wentao Ding;Dong Xue;Xiangnan Li;Yang Zhou;Jiacheng Shen;Jianying Feng;Na Guo;Lijuan Qiu;Han Xing;Jinming Zhao
关键词:100-seed weight; Candidate genes; GWAS; Plant architecture-related traits; Soybean (Glycine max (L.) Merr.)
-
Phenotypic evaluation and genetic dissection of resistance to Phytophthora sojae in the Chinese soybean mini core collection
作者:Jing Huang;Na Guo;Yinghui Li;Jutao Sun;Guanjun Hu;Haipeng Zhang;Yanfei Li;Xing Zhang,Jinming Zhao;Han Xing;Lijuan Qiu
关键词:Soybean mini core collection;Phytophthora sojae;Resistance evaluation;Association mapping;Genetic diversity