数字农科院2.0

Comparative analysis of the genetic diversity of the neutral microsatellite loci and second exon of the goat MHC-DQB1 gene

文献类型: 外文期刊

作者: Gong, Ying;Guo, Yi;He, Yong-Meng;Yuan, Ying;Yang, Bai-Gao;Duan, Xing-Hai;Liu, Cheng-Li;Zhang, Jia-Hua;Hong, Qiong-Hua;Ma, Yue-Hui;Na, Ri-Su;Han, Yan-Guo;Zeng, Yan;Huang, Yong-Fu;Zhao, Yong-Ju;Zhao, Zhong-Quan;Guangxin, E.

作者机构:

关键词: Major histocompatibility complex (MHC); microsatellite markers; goats; genetic diversity; selection

期刊名称: ANIMAL BIOTECHNOLOGY

ISSN: 1049-5398

年卷期: 2021 年

页码:

收录情况: JCR(2021版) ; EI(2021版)

摘要: This study compared and analyzed the genetic diversity and population structure of exon 2 of the DQB1 gene and 13 autosomal neutral microsatellite markers from 14 Chinese goat breeds to explore the potential evolutionary mechanism of the major histocompatibility complex (MHC). A total of 287 haplotypes were constructed from MHC-DQB1 exon 2 from 14 populations, and 82 nucleotide polymorphic sites (SNPs, 31.78%) and 172 heterozygous individuals (79.12%) were identified. The F-ST values of the microsatellites and MHC-DQB ranged between 0.01831-0.26907 and 0.00892-0.38871, respectively. Furthermore, 14 goat populations showed rich genetic diversity in the microsatellite loci and MHC-DQB1 exon 2. However, the population structure and phylogenetic relationship represented by the two markers were different. Positive selection and Tajima's D test results showed the occurrence of a diversified selection mechanism, which was primarily based on a positive and balancing selection in goat DQB. This study also found that the DQB sequences of bovines exhibited trans-species polymorphism (TSP) among species and families. In brief, this study indicated that positive and balancing selection played a major role in maintaining the genetic diversity of DQB, and TSP of MHC in bovines was common, which enhanced the understanding of the MHC evolution.

分类号:

  • 相关文献

[1]Divergent Hd1, Ghd7, And Dth7 A.lleles Control Heading Date A nd Yield Potential Of Japonica Rice In Northeast China. Ye, J, Niu, XJ, Yang, YL, Wang, S, Xu, Q, Yuan, XP, Yu, HY, Wang, YP, Wang, S, Feng, Y, Wei, XH. 2018

[2]Genetic Variation In The Invasive W.eed Mikania Micrantha (Asteraceae) S uggests Highways As Corridors For Its Dispersal In Southern China. Chen, Quan,Geng, Shi-Lei,Geng, Shi-Lei,Cao, Ao-Cheng,Ou-Yang, Can-Bin,Cai, Wen-Li. 2017

[3]Analysis Of Genetic Diversity And P.opulation Structure Of A W orldwide Collection Of Corchorus Olitorius L. Germplasm Using Microsatellite Markers. Yang, ZM, Lu, RK, Dai, ZG, Yan, A, Chen, JQ, Bai, ZB, Xie, DW, Tang, Q, Cheng, CH, Xu, Y, Su, JG. 2018

[4]Genetic Diversity and Association Analysis of Lint Percentage Variation Population in Gossypium Hirsutum L. Based on Microsatellite Markers. Sun, Yali,Pan, Zhaoe,Qu, Yunfang,He, Shoupu,Jia, Yinhua,Wang, Liru,Pang, Baoyin,Li, Hongge,Zhang, Jinlong,Du, Xiongming,Huang, Jinling. 2021

[5]Genetic variability of ten Chinese indigenous goats using MHC-linked microsatellite markers. Guang-Xin, E.,Huang, Yong-Fu,Zhao, Yong-Ju,Na, Ri-Su,Zhang, Jia-Hua,Wu, Xin,Ma, Yue-Hui,Gao, Hui-Jiang.

[6]Structures Of The Mhc-I Molecule Bf2*1501 Disclose The Preferred Presentation Of An H5N1 Virus-Derived Epitope. Li, XY, Zhang, LJ, Liu, YJ, Ma, LZ, Zhang, NZ, Xia, C. 2020

[7]Adaptive And Degenerative Evolution Of T.he S-Phase Kinase-Associated Protein 1 -Like Family In Arabidopsis Thaliana. Gao, Zhenyu,Gao, Zhenyu,Hua, Zhihua,Hua, Zhihua. 2019

[8]Diversity Of Copy Number Variation I.n A Worldwide Population O f Sheep. Yang, L, Xu, LY, Zhou, Y, Liu, M, Wang, L, Kijas, JW, Zhang, HP, Li, L, Liu, GE. 2018

[9]Tabt1, Affecting Starch Synthesis And T.housand Kernel Weight, Underwent S trong Selection During Wheat Improvement. Wang, YM, Hou, J, Liu, H, Li, T, Wang, K, Hao, CY, Liu, HX, Zhang, XY. 2019

[10]Effect Of Divergent Selection For Intramuscular Fat Content On Muscle Lipid Metabolism In Chickens. Liu, L, Cui, HX, Xing, SY, Zhao, GP, Wen, J. 2020

[11]A deletion variant within the FGF5 gene in goats is associated with gene expression levels and cashmere growth. Li Y., Song S., Zhang Z., Liu X., Zhang Y., Guangxin E., Ma Y., Jiang L.. 2022

[12]Genome-wide analyses reveal genetic convergence of prolificacy between goats and sheep. Tao Lin,He Xiaoyun,Jiang Yanting,Liu Yufang,Ouyang Yina,Shen Yezhen,Hong Qionghua,Chu Mingxing. 2021

[13]Identifying Loci With Breeding Potential A.cross Temperate And Tropical A daptation Via Eigengwas And Envgwas. Li, J, Chen, GB, Rasheed, A, Li, DL, Sonder, K, Espinosa, CZ, Wang, JK, Costich, DE, Schnable, PS, Hearne, SJ, Li, HH. 2019

[14]Temporal Expression Of The Kiss1/Gpr54 System In Goats' Testes And Epididymides And Its Spatial Expression In Pubertal Goats. Han, YG, Zhao, YHT, Si, WJ, Jiang, XP, Wu, JY, Na, RS, Han, YQ, Li, K, Yang, LG, Guangxin, E, Zeng, Y, Zhao, YJ, Huang, YF. 2020

[15]Molecular Detection And Identification Of T.ick-Borne Bacteria And Protozoans I n Goats And Wild Siberian Roe Deer (Capreolus Pygargus) From Heilongjiang Province, Northeastern China. Wang, HN, Yang, JF, Mukhtar, MU, Liu, ZJ, Zhang, MH, Wang, XL. 2019

[16]Detection And Molecular Characterization Of P.este Des Petits Ruminants V irus From Outbreaks In Burundi, December 2017-January 2018. Niyokwishimira, A, Baziki, JD, Dundon, WG, Nwankpa, N, Njoroge, C, Boussini, H, Wamwayi, H, Jaw, B, Cattoli, G, Nkundwanayo, C, Ntakirutimana, D, Balikowa, D, Nyabongo, L, Zhang, ZD, Bodjo, SC. 2019

[17]Global Status Of 47 Major W.heat Loci Controlling Yield, Q uality, Adaptation And Stress Resistance Selected Over The Last Century. Zhao, JJ, Wang, ZW, Liu, HX, Zhao, J, Li, T, Hou, J, Zhang, XY, Hao, CY. 2019

[18]Adp-Glucose Pyrophosphorylase Genes, Associated With K.ernel Weight, Underwent Selection D uring Wheat Domestication And Breeding. Hou, J, Li, T, Wang, YM, Hao, CY, Liu, HX, Zhang, XY. 2017

[19]Protection studies of an excretory–secretory protein HcABHD against Haemonchus contortus infection. Mingmin Lu,Xiaowei Tian,Yang Zhang,Wenjuan Wang,Ai-Ling Tian,Kalibixiati Aimulajiang,Lianrui Liu,Charles Li,Ruofeng Yan,Lixin Xu,Xiaokai Song,Xiangrui Li. 2021

[20]Integration Of Conventional And Advanced M.olecular Tools To Track F ootprints Of Heterosis In Cotton. Sarfraz, Zareen,Du, Xiongming,Cai, Zhongmin,Sun, Junling,Geng, Xiaoli,Jia, Yinhua,Zhou, Guanyin,Zhu, Haiyong,Iqbal, Muhammad Shahid,Huang, Aifen,Qu, Yujie,He, Shoupu,Jamshed, Muhammad,Gong, Wenfang,Iqbal, Muhammad Shahid,Zhang, Xuelin,Zhang, Jinbiao,Yi, Xianda,Yang, Jun,Zhang, Xin,Yang, Jinlong,Wang, Qinglian,Xu, Dongyong,Wang, Liru,Pan, Zhaoe,Liu, Jinhai,Li, Lin,Pang, Baoyin,Liu, Hui,Qin, Hongde,Ma, Zhiying,Li, Zhikun. 2018

作者其他论文 更多>>