数字农科院2.0

A new intermediate host of Echinococcus shiquicus in Qinghai-Tibet Plateau, China

文献类型： 外文期刊

作者： Wei Gang Chen;Li Li;Guo Dong Dai;Yao Dong Wu;Nigus Abebe Shumuye;Tharheer Oluwashola Amuda;Xue Qi Tian;Sheng Zhi Gao;Xue Yi Hou;Nian Zhang Zhang;Wen Jun Tian;Lin Sheng Zhang;Le Li;Fu Heng Zhang;Min Kuan Guo;Wen Dong Li;Zhonggecao;Zhaxilamao;Gazangzhuoma;Doukao;Tao Yang;Bao Quan Fu;Hong Yin;Hong Bin Yan;Wan Zhong Jia

作者机构：

关键词： Echinococcus shiquicus;Genetic diversity;Intermediate host;Plateau zokor;Qinghai-Tibet Plateau

期刊名称： Parasitology Research

ISSN： 0932-0113

年卷期： 2025 年 124 卷 6 期

页码：

收录情况： SCIE（2025版）

摘要： Echinococcosis is a severe parasitic zoonosis worldwide distribution, caused by the genus Echinococcus. One of its recently identified species, Echinococcus shiquicus, is believed to be endemic to the Qinghai-Tibet plateau in China. Research has confirmed that Tibetan foxes are the definitive hosts for E. shiquicus, while plateau pikas (Ochotona curzoniae) serve as intermediate hosts. In this study, cyst containing protoscolices was first observed in the lung of plateau zokor (Eospalax baileyi) in the Tibetan Autonomous Prefecture of Gannan, Gansu Province, China. This observation was confirmed using complete sequences of the cox1 and nad1 genes. We also characterized the cysts and examined the genetic diversity of Echinococcus shiquicus collected from the Qinghai-Tibet Plateau region, which includes Gansu Province, Qinghai Province, and the Tibet Autonomous Region. Phylogenetic trees and haplotype analyses for the isolates were constructed using the maximum likelihood method in MEGA 7.0.26 and DnaSP v6 software, based on the complete cox1 (1608 bp) and nad1 (897 bp) gene sequences, as well as a concatenated dataset of cox1-nad1 (2505 bp). The cyst containing protoscolices in the lung of plateau zokor was identified as Echinococcus shiquicus. The prevalence of E. shiquicus infection in plateau pikas in Luqu and Maqu counties in Gansu province was found to be 2.38% (3/126) and 3.36% (10/298), respectively, while in plateau zokors, it was 1.61% (1/62). Haplotype analysis, incorporating sequences from previous studies, revealed the presence of 17 haplotypes, indicating significant haplotype diversity in the study areas. The neutrality indices were Tajima’s D = − 1.438 (P > 0.05) and Fu’s Fs = − 3.169 (P > 0.05). This study provides important insights into Echinococcus shiquicus and its associations with plateau zokors and plateau pikas in the Qinghai-Tibet Plateau. We identified plateau zokors as a new natural intermediate host for E. shiquicus, emphasizing the complexity of its transmission dynamics and host interactions within this unique ecosystem. The observed morphological and developmental state differences in cysts between the liver and lung suggest that presence of tissue specificity in different organ. Additionally, the analysis of genetic diversity revealed high intraspecific variability, indicating a complex population structure influenced by various ecological factors.

分类号：

  • 相关文献

[1]Prevalence of Clonorchis sinensis infection in market-sold freshwater fishes in Jinzhou city, Northeastern China. Bao, M.,Wang, S. D.,Tang, F.,Qu, L. D.,Liu, G. H.,Zhou, D. H.,Song, H. Q.,Liu, G. H.,Zou, F. C.. 2012

[2]First report on the phylogenetic relationship, genetic variation of Echinococcus shiquicus isolates in Tibet Autonomous Region, China. 朱国强,,闫鸿斌,,李立,,李文卉,,张念章,,付宝权,,贾万忠. 2020

[3]Echinococcus shiquicus in Qinghai-Tibet plateau: population structure and confirmation of additional endemic areas. Yan, Hong-Bin,Li, Li,Li, Wenhui,Zhu, Guoqiang,Li, Jian-Qiu,Wu, Yantao,Zhang, Nianzhang,Wu, Yaodong,Li, Min,Zhang, Linsheng,Yao, Gang,Tian, Wenjun,Li, Le,Li, Wenjing,Guo, Aimin,Dai, Guodong,Fu, Baoquan,Ohiolei, John Asekhaen,Jia, Wan-Zhong. 2021

[4]Seismic Signaling for Detection of Empty Tunnels in the Plateau Zokor, Eospalax baileyi. Dong K.,Zhou J.,Zhang F.,Dong L.,Chu B.,Hua R.,Hua L.. 2023

[5]Seasonal dynamics and stability of gut antibiotic resistance genes in plateau pika (Ochotona curzoniae) and plateau zokor (Eospalax baileyi). Wang, Yu,Qian, Yuan,Shi, Chenwei,Bi, Jie,Dong, Pengcheng,Zou, Yongqiang,Yang, Yayuan,Tao, Yuanqing,Li, Huan. 2026

[6]Sex-Based Dietary Divergence in Plateau Pikas (Ochotona curzoniae) but Not Plateau Zokors (Eospalax baileyi). Feiyang Xue,Xidong Zhu,Le Qin,Yanjun Guo,Jian Sun,Zhengqian Dang,Limin Hua,Bin Chu,Rui Hua. 2025

[7]Retrieval snow depth by artificial neural network methodology from integrated AMSR-E and in-situ data-A case study in Qinghai-Tibet Plateau. Cao Yungang,Yang Xiuchun,Zhu Xiaohua. 2008

[8]Genetic characterization of Toxoplasma gondii from Qinghai vole, Plateau pika and Tibetan ground-tit on the Qinghai-Tibet Plateau, China. Zhang, Xiao-Xuan,Lou, Zhong-Zi,Huang, Si-Yang,Zhou, Dong-Hui,Jia, Wan-Zhong,Su, Chunlei,Zhu, Xing-Quan,Zhang, Xiao-Xuan,Su, Chunlei,Zhu, Xing-Quan. 2013

[9]Characterization of symbiotic and endophytic bacteria isolated from root nodules of herbaceous legumes grown in Qinghai-Tibet plateau and in other zones of China. Chen, Zhong Yi,Wang, En Tao,Tian, Chang Fu,Sui, Xin Hua,Chen, Wen Xin. 2007

[10]Sensitivity of Grassland Coverage to Climate across Environmental Gradients on the Qinghai-Tibet Plateau. Rihan Wu,Guozheng Hu,Hasbagan Ganjurjav,Qingzhu Gao. 2023

[11]Mapping of lakes in the Qinghai-Tibet Plateau from 2016 to 2021: trend and potential regularity. Zhichong Yang,Si Bo Duan,Xiaoai Dai,Yingwei Sun,Meng Liu. 2022

[12]Regional distribution and migration potential of antibiotic resistance genes in croplands of Qinghai Tibet Plateau. Dagang Song,Xue Tang,Akash Tariq,Kaiwen Pan,Dong Li. 2023

[13]Morphometrical analyses revealed high diversity of the eastern honey bee (Apis cerana) in mountains and islands in China. Ji, Congcong,Shi, Wei,Tang, Jiao,Ji, Ting,Gao, Jinglin,Liu, Feng,Shan, Jinqiong,Chen, Xiao,Chen, Chao. 2023

[14]Gut Virome of the World's Highest-Elevation Lizard Species (Phrynocephalus erythrurus and Phrynocephalus theobaldi) Reveals Versatile Commensal Viruses. Juan Lu,Shixing Yang,Chunmei Wang,Hao Wang,Ga Gong,Yuan Xi,Jiamin Pan,Xiaochun Wang,Jian Zeng,Ju Zhang,Peng Li,Quan Shen,Tongling Shan,Wen Zhang. 2022

[15]Expansion of Cyclophyllidea Biodiversity in Rodents of Qinghai-Tibet Plateau and the “Out of Qinghai-Tibet Plateau” Hypothesis of Cyclophyllideans. Yao Dong Wu,Guo Dong Dai,Li Li,D. Timothy J. Littlewood,John Asekhaen Ohiolei,Lin Sheng Zhang,Ai Min Guo,Yan Tao Wu,Xing Wei Ni,Nigus Abebe Shumuye,Wen Hui Li,Nian Zhang Zhang,Bao Quan Fu,Yong Fu,Hong Bin Yan,Wan Zhong Jia. 2022

[16]Reclamation intensifies the positive effects of warming on N2O emission in an alpine meadow. Zheng Li,Yan Li,Guozheng Hu,Hongbao Wu,Yan Liang,Jun Yan,Shicheng He,Hasbagan Ganjurjav,Qingzhu Gao. 2023

[17]Comparative analysis of gut fungal composition and structure of the yaks under different feeding models. Zhu, Yanbin,Cidan, Yangji,Sun, Guangming,Li, Xin,Shahid, Muhammad Akbar,Luosang, Zhaxi,Suolang, Zhaxi,Suo, Lang,Basang, Wangdui. 2023

[18]Rest-grazing before soil thawing alters the below-ground distribution and extent of rooting in Carex subalpine meadows. Jing, Yuanyuan,Xiao, Hong,Xu, Changlin,Wang, Lin,Chen, Yanzhu,Liu, Yuanyuan,Yu, Xiaojun. 2023

[19]Spatial and temporal dynamics of livestock grazing intensity in the Selinco region: Towards sustainable grassland management. Guilin Xi,Changhui Ma,Fangkun Ji,Hongxin Huang,Haoyan Zhang,Zecheng Guo,Xueyuan Zhang,Sha Zhao,Yaowen Xie. 2024

[20]Spatio-Temporal Dynamics of Vegetation and Its Driving Mechanisms on the Qinghai-Tibet Plateau from 2000 to 2020. Changhui Ma,Si Bo Duan,Wenhua Qin,Feng Wang,Lei He. 2024

作者其他论文 更多>>