数字农科院2.0

Residue Degradation and Risk Assessment of Difenoconazole and Its Metabolite during Tea Growing, Processing and Brewing by Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry Determination

文献类型： 外文期刊

作者： Wang M.;Ning Y.;Hu Y.;Cui X.;Luo F.;Zhou L.;Yu M.;Zhang X.

作者机构：

关键词： degradation;difenoconazole;metabolite;processing;tea;ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS)

期刊名称： Foods

ISSN： 2304-8158

年卷期： 2024 年 13 卷 7 期

页码：

收录情况： SCIE（2024版）

摘要： Residue dissipation and risk assessment of difenoconazole and its metabolite difenoconazole-alcohol during tea growing, processing, and brewing was first investigated by ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). The limits of quantification for both difenoconazole and difenoconazole-alcohol were 0.001 mg/kg in fresh tea leaves and tea, and 0.0002 mg/L in tea infusion. In field trials, the dissipation half-lives of difenoconazole in fresh tea leaves was 1.77 days. After spraying, the residues of difenoconazole-alcohol increased and then gradually dissipated like difenoconazole. After 14 days, the dissipation rates of difenoconazole and difenoconazole-alcohol reached 99%. When fresh tea leaves were harvested on different days, the total processing factors (PFs) of difenoconazole and difenoconazole-alcohol for green tea were 0.86–1.05 and 0.78–0.85, respectively, while the total PFs for black tea were 0.83–1.13 and 0.82–1.66, respectively. Metabolism of difenoconazole was accelerated during tea processing. When brewing black tea, the leaching rates (LRs) of difenoconazole and difenoconazole-alcohol were 8.4–17.9% and 31.8–38.9%, respectively, while when brewing green tea, the LRs were 15.4–23.5% and 30.4–50.6%, respectively. The LRs of difenoconazole and difenoconazole-alcohol in black tea were higher than those in green tea. The potential threat to human health for dietary intake of difenoconazole and difenoconazole-alcohol residues from tea consumption is negligible. However, the dietary risk of difenoconazole in fruits and vegetables that are essential for daily diets is concerning, with a risk probability of 158%. © 2024 by the authors.

分类号：

  • 相关文献

[1]Residue degradation, transfer and risk assessment of pyriproxyfen and its metabolites from tea garden to cup by ultra performance liquid chromatography tandem mass spectrometry. Li, Hongxia,Zhong, Qing,Wang, Min,Luo, Fengjian,Wang, Xinru,Zhou, Li,Zhang, Xinzhong. 2021

[2]Determination of difenoconazole residue in tomato during home canning by UPLC-MS/MS. Dong, Fengshou,Xu, Jun,Liu, Xingang,Li, Jing,Li, Yuanbo,Chen, Xiu,Zheng, Yongquan,Zhang, Changpeng,Shan, Weili. 2012

[3]Residue Determination of Epoxiconazole, Indoxacarb and Difenoconazole in Tea, Tea Infusion and Soil using Ultra High Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry. Zhang Xin-Zhong,Luo Feng-Jian,Chen Zong-Mao,Liu Guang-Ming,Lou Zheng-Yun,Wang Fang,Wu Lu-Chao,Zhang Xin-Zhong,Luo Feng-Jian,Chen Zong-Mao,Liu Guang-Ming,Lou Zheng-Yun,Zhang Xin-Zhong,Luo Feng-Jian,Chen Zong-Mao,Liu Guang-Ming,Lou Zheng-Yun. 2013

[4]Evaluating the enantioselective degradation and novel metabolites following a single oral dose of metalaxyl in mice. Zhang, Ping,Zhu, Wentao,Wang, Dezhen,Wang, Xinru,Wang, Yao,Zhou, Zhiqiang,Qiu, Jing.

[5]Enantioselective separation and transformation of metalaxyl and its major metabolite metalaxyl acid in tomato and cucumber. Dong, Fengshou,Liu, Xingang,Xu, Jun,Chen, Xiu,Han, Yongtao,Cheng, Youpu,Zheng, Yongquan,Jian, Qiu.

[6]Residue behavior and safety evaluation of pymetrozine in tea. Huan Yu,Hezhi Sun,Xinru Wang,Yabo Liang,Mingming Guo,Jiawei Yu,Mei Yang,Xinzhong Zhang,Fengjian Luo,Li Zhou. 2021

[7]Tea: From Historical Documents to Modern Technology. Liang Zhang,Yongquan Xu,Zhonghua Liu. 2023

[8]Selecting a representative tea for risk assessment of pesticide residue in tea:Afidopyropen as a case. Mingming Guo,Zhaoqun Li,Yujie Qin,Kexin Qian,Chi Su,Jiawei Yu,Hezhi Sun,Xinzhong Zhang,Xinru Wang,Mei Yang,Fengjian Luo,Zongmao Chen,Li Zhou. 2025

[9]Enantioselective Dissipation of Acephate and Its Metabolite, Methamidophos, during Tea Cultivation, Manufacturing, and Infusion. Pan, Rong,Chen, Hongping,Wang, Chen,Wang, Qinghua,Jiang, Ying,Liu, Xin,Pan, Rong,Chen, Hongping,Wang, Chen,Wang, Qinghua,Jiang, Ying,Liu, Xin.

[10]Simultaneous Quantitative Determination of Residues of Pyriproxyfen and Its Metabolites in Tea and Tea Infusion Using Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry. Li H.,Zhong Q.,Wang X.,Luo F.,Zhou L.,Chen Z.,Zhang X.. 2022

[11]Residue analysis and risk assessment of cyflumetofen and its three metabolites from fresh tea leaf to tea infusion through purification with new nano adsorbents and determination by ultra-performance liquid chromatography-tandem mass spectrometry. Yating Ning,Yue Hu,Fengjian Luo,Xiangyun Wang,Li Zhou,Bingjun Han,Liezhong Chen,Xinzhong Zhang. 2025

[12]Residue pattern and risk assessment of validamycin A and spinosyn A in tea using hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry. Aiping Li,Chen Wang,Yunfeng Chai,Zhiming Huang,Binbin Yao,Chengyin Lu,Miao Yu,Hongping Chen. 2025

[13]黑麦草-白三叶人工草地退化趋势研究(英文). 张建波,李相林,万里强,陈瑞祥,赵相勇,陈伟,陈国南. 2009

[14]Concentrations and dissipation of difenoconazole and fluxapyroxad residues in apples and soil, determined by ultrahigh-performance liquid chromatography electrospray ionization tandem mass spectrometry. Jia, Chunhong,Zhao, Ercheng,Chen, Li,Yu, Pingzhong,Jing, Junjie,He, Min,Zheng, Yongquan.

[15]Simultaneous enantioselective determination of triazole fungicide difenoconazole and its main chiral metabolite in vegetables and soil by normal-phase high-performance liquid chromatography. Dong, Fengshou,Cheng, Youpu,Liu, Xingang,Xu, Jun,Li, Yuanbo,Chen, Xiu,Kong, Zhiqiang,Zheng, Yongquan,Cheng, Youpu.

[16]Metabolomics And Transcriptomics Reveal The T.oxicity Of Difenoconazole To T he Early Life Stages Of Zebrafish (Danio Rerio). Teng, MM, Zhu, WT, Wang, DZ, Qi, SZ, Wang, Y, Yan, J, Dong, K, Zheng, MQ, Wang, CJ. 2018

[17]Bioavailability assessment of difenoconazole to earthworms (Eisenia fetida) in soil by oleic acid-embedded cellulose acetate membrane. Yajie Chen,Xiaojian Feng,Xingang Liu,Lan Zhang,Liangang Mao,Lizhen Zhu,Yongquan Zheng. 2023

[18]Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior. Xiangguang Chen,Junyue Zheng,Jie Zhang,Manman Duan,Hao Xu,Wentian Zhao,Yang Yang,Chengju Wang,Yong Xu. 2022

[19]Ecological risk assessment for difenoconazole in aquatic ecosystems using a web-based interspecies correlation estimation (ICE)-species sensitivity distribution (SSD) model. Chao Shen,Xinglu Pan,Xiaohu Wu,Jun Xu,Fengshou Dong,Yongquan Zheng. 2022

[20]Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish. Changsheng Li,Shankui Yuan,Yanming Zhou,Xuefeng Li,Liusheng Duan,Lan Huang,周晓今,Yongqiang Ma,Sen Pang. 2022

作者其他论文 更多>>