数字农科院2.0

Threshold Level Of Riemerella Anatipestifer C.rossing Blood-Brain Barrier And E xpression Profiles Of Immune-Related Proteins In Blood And Brain Tissue From Infected Ducks

文献类型： 外文期刊

作者： Li, SD; Gong, XW; Chen, QW; Zheng, FY; Ji, G; Liu, YS

作者机构：

关键词： Riemerella anatipestifer; Bacterial burden; Immune-related proteins; Blood; Brain

期刊名称： VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

ISSN： 0165-2427

年卷期： 2018 年 200 卷

页码：

收录情况： JCR（2021版）

摘要： Riemerella anatipestifer (R. anatipestifer) is a Gram-negative bacterium that crosses the blood-brain barrier (BBB: and causes meningitis with neurological symptoms in infected ducks. A threshold level of bacteremia must be reached before the BBB can be breached. In this study, the bacterial burden and expression profiles of immune. related proteins in blood and brain tissue samples from R. anatipestifer-infected ducks were investigated. The data showed that R. anatipestifer could cross the BBB with low-level bacteremia of 7.5 x 10(2) CFU/ml in infectec blood. Analysis of immune-related proteins revealed that IL-4, IL-17A, IL-17D, TLR3, TLR4, TLR7, and TGF-beta ir blood, as well as IL-1 beta, IL-2, IL-4, IL-17A, IL-17D, IL-17F, TLR3, TLR4, and TGF-beta in brain tissue were upre. gulated at an early stage in infection. The expression levels of Th1 and Th17-specific cytokines were significantly higher than those of Th2-specific cytokines, which indicated that mainly Th1 and Th17 immune responses were induced during R. anatipestifer infection.

分类号：

  • 相关文献

[1]Vitamin E Supplementation Ameliorates Newcastle D.isease Virus-Induced Oxidative Stress A nd Alleviates Tissue Damage In The Brains Of Chickens. Rehman, ZU, Qiu, XS, Sun, YJ, Liao, Y, Tan, L, Song, CP, Yu, SQ, Ding, Z, Munir, M, Nair, V, Meng, CC, Ding, C. 2018

[2]Phosphoproteomic basis of neuroplasticity in the antennal lobes influences the olfactory differences between A. mellifera and A. cerana honeybees. Meng L., Altaye S.Z., Feng M., Hu H., Han B., Li J.. 2022

[3]Mirna And Circrna Expression Patterns In Mouse Brain During Toxoplasmosis Development. Zhou, CX, Ai, K, Huang, CQ, Guo, JJ, Cong, H, He, SY, Zhu, XQ. 2020

[4]Brain Organization Of Apolygus Lucorum: A. Hemipteran Species With P rominent Antennal Lobes. Zhao, Xin:Cheng,Li, Guo:Ping,Zhang, Yong:Jun,Xie, Gui:Ying,Chang, Ya:Jun,Chen, Wen:Bo,Berg, Bente G.,Feng, Hong:Qiang,Liu, Xiao:Lan,Ma, Bai:Wei. 2019

[5]Different Diets Change The Expression Of Bovine Serum Extracellular Vesicle-Mirnas. Quan, SY, Nan, XM, Wang, K, Jiang, LS, Yao, JH, Xiong, BH. 2019

[6]Native Nanodiscs From Blood Inhibit P.ulmonary Fibrosis. Sun, AQ, Lai, ZY, Zhao, MY, Mu, L, Hu, XG. 2019

[7]Arginine Improves The Color Stability O.f Hemoglobin Powder During F reeze-Drying And Storage. Hou, CL, Song, X, Li, Z, Wang, WT, Shen, QW, Zhang, DQ. 2019

[8]Accumulation And Depletion Of Cadmium I.n The Blood, Milk, H air, Feces, And Urine Of Cows During And After Treatment. Su, CY, Zhang, JM, Li, ZT, Zhao, QY, Liu, KD, Sun, YD, Wang, JH. 2017

[9]Host-seeking behavior and fecundity of the female Aedes aegypti to human blood types. Khan S.A., Ombugadu A., Ahmad S.. 2022

[10]Fast and High Sensitive Analysis of Lead in Human Blood by Direct Sampling Hydride Generation Coupled with in situ Dielectric Barrier Discharge Trap. Meitong LIU,Lan DING,Jixin LIU,Xuefei MAO,Xing NA,Yunbin SHAO. 2021

[11]A Novel Gas Liquid Separator F.or Direct Sampling Analysis O f Ultratrace Arsenic In Blood Sample By Hydride Generation In-Situ Dielectric Barrier Discharge Atomic Fluorescence Spectrometry. Liu, MT, Liu, TP, Mao, XF, Liu, JX, Na, X, Ding, L, Qian, YZ. 2019

[12]Tributyrin administration improves intestinal development and health in pre-weaned dairy calves fed milk replacer. Liu S., Wu J., Wu Z., Alugongo G.M., Zahoor Khan M., Li J., Xiao J., He Z., Ma Y., Li S., Cao Z.. 2022

[13]Development of multiplex PCR assay for rapid detection of Riemerella anatipestifer, Escherichia coli, and Salmonella enterica simultaneously from ducks. Hu, Qinghai,Tu, Jing,Han, Xiangan,Zhu, Yinyu,Ding, Chan,Yu, Shengqing,Ding, Chan,Yu, Shengqing. 2011

[14]Construction of a shuttle vector for use in Riemerella anatipestifer. Hu, Qinghai,Miao, Shuang,Ni, Xintao,Lu, Fengying,Yu, Hui,Xing, Linlin,Jiang, Pan. 2013

[15]Genome-wide mining of potential virulence-associated genes in Riemerella anatipestifer using random transposon mutagenesis. Ni, Xintao,Jiang, Pan,Xing, Linlin,Ou, Changcan,Yu, Hui,Qi, Jingjing,Sun, Bingqing,Cui, Junsheng,Hu, Qinghai,Wang, Guijun.

[16]The M949_1556 gene plays a role on the bacterial antigenicity and pathogenicity of Riemerella anatipestifer. Zou, Jiechi,Wang, Xiaolan,Tian, Mingxing,Cao, Shoulin,Hou, Wanwan,Wang, Shaohui,Han, Xiangan,Ding, Chan,Yu, Shengqing.

[17]Characterization and cross-protection evaluation of M949_1603 gene deletion Riemerella anatipestifer mutant RA-M1. Zou, Jiechi,Wang, Xiaolan,Ding, Chan,Tian, Mingxing,Han, Xiangan,Wang, Shaohui,Yu, Shengqing.

[18]Effects of two efflux pump inhibitors on the drug susceptibility of Riemerella anatipestifer isolates from China. Li Ya-fei,Jiang Hong-xia,Zhang Ya-nan,Zhao Li-qing,Gu Peng,Wang Li-qiao,Zeng Zhen-ling,Xiang Rong,Sun Na. 2016

[19]Immunoproteomics analysis of whole cell bacterial proteins of Riemerella anatipestifer. Hu, Qinghai,Ding, Chan,Tu, Jing,Wang, Xiaolan,Han, Xiangan,Duan, Yunbing,Yu, Shengqing,Yu, Shengqing.

[20]Levamisole enhances immunity in ducklings vaccinated against Riemerella anatipestifer. Zhang, Yuewei,Zeng, Xiangfan,Wu, Wenxue,Chen, Huiling,Wang, Peng,Li, Jinxiang.

作者其他论文 更多>>