数字农科院2.0

Mechanism And Complex Roles Of Hsc70 In Viral Infections

文献类型： 外文期刊

作者： Wang, Z; Li, YT; Yang, X; Zhao, J; Cheng, YN; Wang, JK

作者机构：

关键词： Hsc70; Virus; Infection; Regulatory Mechanism; Role

期刊名称： FRONTIERS IN MICROBIOLOGY

ISSN： 1664-302X

年卷期： 2020 年 11 卷

页码：

收录情况： JCR（2021版）

摘要： Heat shock cognate 71-kDa protein (HSC70), a constitutively expressed molecular chaperon within the heat shock protein 70 family, plays crucial roles in maintaining cellular environmental homeostasis through implicating in a wide variety of physiological processes, such as ATP metabolism, protein folding and transporting, antigen processing and presentation, endocytosis, and autophagy. Notably, HSC70 also participates in multiple non-communicable diseases and some pathogen-caused infectious diseases. It is known that virus is an obligatory intracellular parasite and heavily relies on host machineries to self-replication. Undoubtedly, HSC70 is a striking target manipulated by virus to ensure the successful propagation. In this review, we summarize the recent advances of the regulatory mechanisms of HSC70 during viral infections, which will be conducive to further study viral pathogenesis.

分类号：

  • 相关文献

[1]Washed Microbiota Transplantation Vs. Manual Fecal Microbiota Transplantation: Clinical Findings, Animal Studies And In Vitro Screening. Zhang, Faming,Yin, Haoran,Zhang, Faming,Zhang, Faming,Wang, Huiquan,Marcella, Cicilia,Lu, Gaochen,Shen, Quan,Marcella, Cicilia,Zhao, Zhe,Chen, Yaoyao,Zhang, Ting,Cheng, Lei,Chen, Yaoyao,Zhang, Ting,Cui, Bota,Li, Pan,Cheng, Lei,Cui, Bota,Lu, Gaochen,Ji, Guozhong,Ji, Guozhong,Liu, Yafei,Li, Pan,Liu, Yafei. 2020

[2]Identification of heat shock cognate protein 70 gene (Alhsc70) of Apolygus lucorum and its expression in response to different temperature and pesticide stresses. Zhao, Jing,Sheng, Yang,Bai, Li-Xin,Tan, Yongan,Xiao, Liu-Bin,Xu, Guang-Chun,Sun, Yang,Zhang, Yong-Jun,Xiao, Ying-Fang. 2016

[3]The TGEV Membrane Protein Interacts with HSC70 To Direct Virus Internalization through Clathrin-Mediated Endocytosis. Zhaoyang Ji,Dong, Hui,Jiao, Ruixue,Zhu, Xiaoyuan,Shi, Hongyan,Chen, Jianfei,Shi, Da,Liu, Jianbo,Jing, Zhaoyang,Zhang, Jialin,Wang, Xiaobo,Ye, Dandan,Zhang, Jiyu,Zhang, Xin,Feng, Li. 2023

[4]Sialidases From Clostridium Perfringens And Their Inhibitors. Wang, YH. 2020

[5]Phosphorylation plays positive roles in regulating the inhibitory ability of calpastatin to calpain. Du M., Li X., Zhang D., Li Z., Hou C., Ren C., Bai Y.. 2022

[6]The Maize Wrky Transcription Factor Z.mwrky40 Confers Drought Resistance I n Transgenic Arabidopsis. Wang, CT, Ru, JN, Liu, YW, Yang, JF, Li, M, Xu, ZS, Fu, JD. 2018

[7]Exploiting Genic Male Sterility in Rice: From Molecular Dissection to Breeding Applications. Adil Abbas,Ping Yu,Lianping Sun,Zhengfu Yang,Daibo Chen,Shihua Cheng,Liyong Cao. 2021

[8]Identification Of Differentially Expressed Genes A.nd Pathways For Intramuscular F at Metabolism Between Breast And Thigh Tissues Of Chickens. Cui, HX, Zheng, MQ, Zhao, GP, Liu, RR, Wen, J. 2018

[9]A 5-Methylcytosine Site Of Growth D.ifferentiation Factor 9 (Gdf9) G ene Affects Its Tissue-Specific Expression In Sheep. Pan, ZY, Wang, XY, Di, R, Liu, QY, Hu, WP, Cao, XH, Guo, XF, He, XY, Lv, SJ, Li, FK, Wang, H, Chu, MX. 2018

[10]Regulation Of Ascorbate Accumulation And Metabolism In Lettuce By The Red:Blue Ratio Of Continuous Light Using Leds. Zha, LY, Liu, WK, Yang, QC, Zhang, YB, Zhou, CB, Shao, MJ. 2020

[11]Genetic Regulation and Breeding Application of Medium- Chain Fatty Acids Metabolism in Rice. Zubair M, Tong X, Ashraf A, Li H, Li G, Xin A, Chen J, Wang Y, Li Z, Huang J, Cheng Y, Zhang J*, Ying J*. 2025

[12]Loquat Is A New Natural Host Of Apple Stem Grooving Virus And Apple Chlorotic Leaf Spot Virus In China. Li, Ruhui,Li, Min,Qiu, Yuanjian,Li, Min,Wu, Di,Wu, Jiaxing,Cao, Mengji,Zhang, Song,Zhang, Song,Cao, Mengji,Xuan, Zhiyou,Xuan, Zhiyou,Liu, Qiyan,Wu, Jiaxing,Liu, Qiyan,Qiu, Yuanjian. 2019

[13]Animal Rabies In The People'S R.epublic Of China. Tu, C.,Wang, Y.,Feng, Y.,Tu, C.. 2018

[14]Dendritic Cell Harmonised Immunity To P.oultry Pathogens; A Review. Rehman, ZU, Umar, S, Meng, C, Ullah, Z, Riaz, F, Rehman, SU, Ding, C. 2017

[15]Interactions between commensal bacteria and viral infection: insights for viral disease control in farmed animals. Chao Ran,Yu Li,Xufa Ma,Yadong Xie,Mingxu Xie,Yuting Zhang,Wei Zhou,Yalin Yang,Zhen Zhang,Li Zhou,Kaijian Wei,Zhigang Zhou. 2021

[16]The C/Ebp Homologous Protein (Chop) T.ranscription Factor Functions In E ndoplasmic Reticulum Stress-Induced Apoptosis And Microbial Infection. Hu, H, Tian, MX, Ding, C, Yu, SQ. 2019

[17]Genomic, Morphological And Biological Traits O.f The Viruses Infecting M ajor Fruit Trees. Umer, M, Liu, JW, You, HF, Xu, C, Dong, KL, Luo, N, Kong, LH, Li, XP, Hong, N, Wang, GP, Fan, XD, Kotta-Loizou, I, Xu, W. 2019

[18]Chicken Galectin-1B Inhibits Newcastle Disease V.irus Adsorption And Replication T hrough Binding To Hemagglutinin-Neuraminidase (Hn) Glycoprotein. Sun, JF, Han, ZX, Qi, TM, Zhao, R, Liu, SW. 2017

[19]Porcine Reproductive And Respiratory Syndrome V.irus Counteracts Type I I nterferon-Induced Early Antiviral State By Interfering Irf7 Activity. Liu, K, Ma, GN, Liu, XQ, Lu, Y, Xi, SM, Ou, AN, Wei, JC, Li, BB, Shao, DH, Li, YM, Qiu, YF, Miao, DN, Ma, ZY. 2019

[20]Mast Cells And Innate Immunity: M.aster Troupes Of The A vian Immune System. Rehman, ZU, Meng, C, Umar, S, Mahrose, KM, Ding, C, Munir, M. 2017

作者其他论文 更多>>