数字农科院2.0

Serotype shift of a 793/B genotype infectious bronchitis coronavirus by natural recombination

文献类型： 外文期刊

作者： Zhang, Tingting;Han, Zongxi;Xu, Qianqian;Wang, Qiuling;Gao, Mengying;Wu, Wei;Shao, Yuhao;Li, Huixin;Kong, Xiangang;Liu, Shengwang

作者机构：

关键词： Infectious bronchitis coronavirus;Recombination;Genotype;Serotype;Vaccination-challenge test

期刊名称： INFECTION GENETICS AND EVOLUTION

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： An infectious bronchitis coronavirus, designated as ck/CH/LHLJ/140906, was isolated from an infectious bronchitis virus (IBV) strain H120-vaccinated chicken flock, which presented with a suspected infectious bronchitis virus (IBV) infection. A phylogenetic analysis based on the Si gene clustered ck/CH/LHLJ/140906 with the 793/B group; however, a pairwise comparison showed that the 5' terminal of the S1 gene (containing hypervariable regions I and II) had high sequence identity with the H120 strain, while the 3' terminal sequence was very similar to that of IBV 4/91 strain. A SimPlot analysis of the complete genomic sequence, which was confirmed by a phylogenetic analysis and nucleotide similarities using the corresponding gene fragments, suggested that isolate ck/CH/LHLJ/140906 emerged from multiple recombination events between parental IBV strains 4/91 and H120. Although the isolate ck/CH/LHLJ/ 140906 had slightly higher S1 amino acid sequence identity to strain 4/91 (88.2%) than to strain H120 (86%), the serotype of the virus was more closely related to that of the H120 strain (32% antigenic relatedness) than to the 4/91 strain (15% antigenic relatedness). Whereas, vaccination of specific pathogen-free chickens with the 4/91 vaccine provided better protection against challenge with ck/CH/LHLJ/ 140906 than did vaccination with the H120 strain according to the result of virus re-isolation. As the spike protein, especially in the hypervariable regions of the S1 domain, of IBVs contains viral neutralizing epitopes, the results of this study showed that recombination of the Si domain resulted in the emergence of a new serotype. (C) 2015 Elsevier B.V. All rights reserved.

分类号： R1

  • 相关文献

[1]Altered pathogenicity of a tl/CH/LDT3/03 genotype infectious bronchitis coronavirus due to natural recombination in the 5 '-17 kb region of the genome. Han, Zongxi,Zhang, Tingting,Xu, Qianqian,Gao, Mengying,Chen, Yuqiu,Wang, Qiuling,Zhao, Yan,Shao, Yuhao,Li, Huixin,Kong, Xiangang,Liu, Shengwang.

[2]Genetic, antigenic, and pathogenic characteristics of avian infectious bronchitis viruses genotypically related to 793/B in China. Han, Zongxi,Zhao, Wenjun,Chen, Yuqiu,Xu, Qianqian,Sun, Junfeng,Zhang, Tingting,Zhao, Yan,Liang, Shuling,Gao, Mengying,Wang, Qiuling,Kong, Xiangang,Liu, Shengwang.

[3]Molecular and antigenic characteristics of Massachusetts genotype infectious bronchitis coronavirus in China. Chen, Lingfeng,Zhang, Tingting,Han, Zongxi,Liang, Shuling,Xu, Yang,Xu, Qianqian,Chen, Yuqiu,Zhao, Yan,Shao, Yuhao,Li, Huixin,Wang, Kexiong,Kong, Xiangang,Liu, Shengwang.

[4]Identification and molecular characterization of a novel serotype infectious bronchitis virus (GI-28) in China. Chen, Yuqiu,Jiang, Lei,Zhao, Wenjun,Liu, Liangliang,Zhao, Yan,Shao, Yuhao,Li, Huixin,Han, Zongxi,Liu, Shengwang.

[5]Serotype, antigenicity, and pathogenicity of a naturally recombinant TW I genotype infectious bronchitis coronavirus in China. Gao, Mengying,Wang, Qiuling,Zhao, Wenjun,Chen, Yuqiu,Zhang, Tingting,Han, Zongxi,Xu, Qianqian,Kong, Xiangang,Liu, Shengwang.

[6]Genome characterization, antigenicity and pathogenicity of a novel infectious bronchitis virus type isolated from south China. Jiang, Lei,Zhao, Wenjun,Han, Zongxi,Chen, Yuqiu,Zhao, Yan,Sun, Junfeng,Li, Huixin,Shao, Yuhao,Liu, Liangliang,Liu, Shengwang.

[7]Genotyping of Haemophilus Parasuis Isolated from Northwest China Using PCR-RFLP Based on the ompA Gene. Chu, Yue-Feng,Gao, Peng-Chen,Zhao, Ping,He, Yin,Zhang, Nian-Zhang,Liu, Yong-Sheng,Liu, Ji-Xing,Lu, Zhong-Xin.

[8]ComparativecharacterizationofmicroRNAprofilesofdifferentgenotypesofToxoplasmagondii. 周东辉,MinjunXu,SiyangHuang,FurongZhao,AlasdairJ.Nisbet,HuiqunSong,XingquanZhu. 2013

[9]Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection. Sun, Junfeng,Han, Zongxi,Shao, Yuhao,Cao, Zhongzan,Kong, Xiangang,Liu, Shengwang.

[10]Characterization of a recombinant coronavirus infectious bronchitis virus with distinct S1 subunits of spike and nucleocapsid genes and a 3 ' untranslated region. Liu, Xiaoli,Ma, Huijie,Xu, Qianqian,Sun, Nana,Han, Zongxi,Sun, Chuyang,Guo, Hongbo,Shao, Yuhao,Kong, Xiangang,Liu, Shengwang. 2013

[11]Identification of the avian infectious bronchitis coronaviruses with mutations in gene 3. Liu, Shengwang,Zhang, Qingxia,Chen, Jianfei,Han, Zongxi,Shao, Yuhao,Kong, Xiangang,Tong, Guangzhi. 2008

[12]Genetic, Antigenic, And Pathogenic Characteristics O.f Avian Infectious Bronchitis V iruses Genotypically Related To 793/B In China. Han, ZX, Zhao, WJ, Chen, YQ, Xu, QQ, Sun, JF, Zhang, TT, Zhao, Y, Liang, SL, Gao, MY, Wang, QL, Kong, XG, Liu, SW. 2017

[13]Identification And Molecular Characterization Of A. Novel Serotype Infectious B ronchitis Virus (Gi-28) In China. Chen, YQ, Jiang, L, Zhao, WJ, Liu, LL, Zhao, Y, Shao, YH, Li, HX, Han, ZX, Liu, SW. 2017

[14]Genome Characterization, Antigenicity And Pathogenicity O.f A Novel Infectious B ronchitis Virus Type Isolated From South China. Jiang, L, Zhao, WJ, Han, ZX, Chen, YQ, Zhao, Y, Sun, JF, Li, HX, Shao, YH, Liu, LL, Liu, SW. 2017

[15]New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China. Dong C.-L.,Che R.-X.,Wu T.,Qu Q.-W.,Chen M.,Zheng S.-D.,Cai X.-H.,Wang G.,Li Y.-H.. 2023

[16]Molecular Epidemiology of Extraintestinal Pathogenic Escherichia coli Causing Hemorrhagic Pneumonia in Mink in Northern China. Ying Yu,Bo Hu,Huanhuan Fan,Hailing Zhang,Shizhen Lian,Hongye Li,Shuangshuang Li,Xijun Yan,Shaohui Wang,Xue Bai. 2021

[17]Molecular Epidemiology of Extraintestinal Pathogenic Escherichia coli Causing Hemorrhagic Pneumonia in Mink in Northern China. Ying Yu,Bo Hu,Huanhuan Fan,Hailing Zhang,Shizhen Lian,Hongye Li,Shuangshuang Li,Xijun Yan,Shaohui Wang,Xue Bai. 2021

[18]Bovine Herpesvirus-4 Based Vaccine Provides Protective Immunity against Streptococcus suis Disease in a Rabbit Model. Nihua Dong,Hester Nichols,Qing Sun,Xiaojun Chen,Jiayang Zheng,Zhixin Guan,Hailong Zhang,Andrew Davison,Yvonne Wezel,Zongjie Li,Beibei Li,Ke Liu,Donghua Shao,Yafeng Qiu,Jianhe Sun,Xiangdong Li,Mathew Upton,Zhiyong Ma,Michael A. Jarvis,Jianchao Wei. 2023

[19]An Epidemiological Study on Salmonella in Tibetan Yaks from the Qinghai–Tibet Plateau Area in China. Dengyu Li,Kaiqin Zhang,Xiaofeng Xue,Zhanchun Bai,La Yang,Jingjing Qi,Sizhu Suolang. 2024

[20]Immunogenic cross-reactivity between different serotypes novel duck reoviruses: Evaluation of cross-protection provided by mono or bivalent vaccine. Dong Huang,Yu Shao,Ruizhi Wang,Sijia Liu,Shilei Zhang,Shijun Bao. 2025

作者其他论文 更多>>