数字农科院2.0

Comparative phospholipid profiling of human milk and infant formulas using LC-MS/MS and a multi-parameter similarity evaluation model

文献类型： 外文期刊

作者： Huiquan Zhu;Marie Laure Fauconnier;Hong Zhang;Xuebing Xu;Ruihua Guo;Shuwen Zhang;Xiaodan Wang;Jiaping Lv;Xiaoyang Pang;Yunna Wang

作者机构：

关键词： Evaluation model;Human milk;Infant formulas;Phospholipid

期刊名称： Food Chemistry

ISSN： 0308-8146

年卷期： 2026 年 504 卷

页码：

收录情况： SCIE（2025版） ; ; EI（2025版）

摘要： Human milk phospholipid (HMPL) plays an indispensable role in infant growth, while there are few studies focused on the comprehensive phospholipid composition between human milk and infant formula. In this study, LC-MS/MS and a similarity evaluation model were used to compare phospholipid composition from human milk and infant formula. The results showed that the number of phospholipid molecules detected in HM (137) was higher than that in CIFs (86) and GIFs (77). Furthermore, the similarity evaluation showed that although the average comprehensive similarity score for CIFs (65.68) was higher than that for GIFs (53.62), their phospholipid compositions differed significantly from HMPLs. Therefore, these results not only deepen our understanding of HM phospholipids but also provide a new scientific basis for the development of infant formulas.

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