Exploring the intricacies of antimicrobial resistance: Understanding mechanisms, overcoming challenges, and pioneering innovative solutions
文献类型: 外文期刊
作者: Shahbaz Ul Haq;Wang Ling;Amjad Islam Aqib;Huang Danmei;Muhammad Tahir Aleem;Mahreen Fatima;Saad Ahmad;Fenfei Gao
作者机构:
关键词: Antibiotic crisis;Antimicrobial resistance;Global health;Innovative therapies;Multidrug-resistant bacteria;Precision medicine
期刊名称: European Journal of Pharmacology
ISSN: 0014-2999
年卷期: 2025 年 998 卷
页码:
收录情况: SCIE(2025版)
摘要: Antimicrobial resistance (AMR) poses a growing global threat. This review examines AMR from diverse angles, tracing the story of antibiotic resistance from its origins to today's crisis. It explores the rise of AMR, from its historical roots to the urgent need to counter this escalating menace. The review explores antibiotic classes, mechanisms, resistance profiles, and genetics. It details bacterial resistance mechanisms with illustrative examples. Multidrug-resistant bacteria spotlight AMR's resilience. Modern AMR control offers hope through precision medicine, stewardship, combination therapy, surveillance, and international cooperation. Converging traditional and innovative treatments presents an exciting frontier as novel compounds seek to enhance antibiotic efficacy. This review calls for global unity and proactive engagement to address AMR collectively, emphasizing the quest for innovative solutions and responsible antibiotic use. It underscores the interconnectedness of science, responsibility, and action in combatting AMR. Humanity faces a choice between antibiotic efficacy and obsolescence. The call is clear: unite, innovate, and prevail against AMR.
分类号:
- 相关文献
作者其他论文 更多>>
-
Green Synthesis of Dual Function CS/Ag Nanoformulation for Implant Protection against Pseudomonas aeruginosa Biofilm
作者:Humaira Khan;Bushra Uzair;Fehmida Fasim;Mahreen Fatima;Azmat Ali Khan;Zukhra Abbasi;Sabiha Fatima
关键词:Biofilm;Cannabis plants (Cannabis sativa);Chitosan/Silver nanoformulation;Green synthesis;Orthopaedic implants (Herbert screw);Pseudomonas aeruginosa;Silver-nanoparticles
-
Comparative Efficacy of Zinc Oxide Nanoparticles and Citric Acid on Surgically Incised Wound in Rabbit
作者:Rizwan Abdul Aleem;Asad Khan;Shafqat Naeem;Muhammad Tahir Aleem;Iftikhar Ali Khan;Abdul Qadeer;Shakeel Ahmed;Sadaf Aslam;Ashar Mehfooz
关键词:Citric acid;Collagen;Rabbits;Wound healing;Zinc oxide nanoparticles
-
Global Scale Insights into Genetic Variation in Mitochondrial cox1 and nad1 Genes of Clonorchis sinensis
作者:Shahbaz Ul Haq;Talha Javaid;Majed H. Wakid;Muhammad Wasim Usmani;Muhammad Saqib;Muhammad Abdullah Malik;Shujaat Hussain;Safia Obaidur Rab;Mohd Saeed;Asif Ali Butt;Fenfei Gao;Hong Bin Yan;Li Li;Mughees Aizaz Alvi
关键词:Clonorchis sinensis;Diversity indices;Epidemiology;Haplotypes;Neutrality indices;Population structure
-
Emerging threat of antimicrobial resistance determinants and plasmid replicon types acquisition by Escherichia coli of poultry and other food-producing animal origin in China: local findings with global implications
作者:Muhammad Shoaib;Muhammad Fazal Hameed;Amjad Islam Aqib;Weiwei Wang;Qing Wang;Shengyi Wang;Wanxia Pu
关键词:Antibiotic resistance genes;Epidemiology;Escherichia coli;Food-producing animals;Plasmid replicon types
-
Enhancing Folate Content in Japonica Rice Through Co-expression of OsADCS and OsGTPCHI Indica Alleles
作者:Lai Changkai;Hu Shikai;Jiao Guiai;Wang Ling;Shao Gaoneng;Zhao Fengli;Xie Lihong;Wei Xiangjin;Lü Yusong;Sheng Zhonghua;Tang Shaoqing;Hu Peisong
关键词:biofortification;endosperm-specific expression;folate content;grain;Oryza sativa;OsADCS;OsGTPCHI
-
Effects of Nitrogen-Regulating Gene AreA on Growth, Pathogenicity, and Fumonisin Synthesis of Fusarium proliferatum
作者:Sun Lei;Chen Xu;Zhou Qianya;Zhang Tianlei;Yu Qian;Liu Lianmeng;Huang Shiwen;Wang Ling
关键词:
-
Fermented Astragalus Powder, a New Potential Feed Additive for Broilers to Improve the Growth Performance and Health
作者:Songwei Han;Guowei Xu;Kang Zhang;Saad Ahmad;Lei Wang;Fubin Chen;Jiahui Liu;Xueyan Gu;Jianxi Li;Jingyan Zhang
关键词:antioxidant capacity;fermentation;immune function;intestinal microbiota;traditional Chinese medicine