数字农科院2.0

Landscape and m6A post-transcriptional regulation of soybean proteome

文献类型： 外文期刊

作者： Yang, Qing;Hou, Zhi-Yang;Li, Linxia;Wang, Leili;Li, Shang-Tong;Li, Yaping;Zhang, Xuemin;Huang, Huanwei;Ke, Yunzhuo;Ma, Xiaofei;Wu, Zexuan;Liu, Zhi;Shi, Xiaolei;Liu, Chaofan;Meng, Chen;Du, Hai;Chen, Mingxun;Gu, Xiaofeng;Yan, Zhe;Wang, Faming;Luo, Xiao;Yan, Long;Liang, Zhe

作者机构：

期刊名称： CELL GENOMICS

ISSN： 2666-979X

年卷期： 2025 年 5 卷 9 期

页码：

收录情况： ESCI（2025版）

摘要： The soybean is a critical source of vegetable protein, but its proteome remains undercharacterized. Here, we quantify 12,855 proteins across 14 soybean organs using 4D data-independent acquisition mass spectrometry (4D-DIA-MS), creating the most extensive soybean proteome dataset to date. Organ-specific protein expression and co-expression analyses highlight functional specificity with significant differences in protein-transcript abundance across organs. We also map N6-methyladenosine (m6A) modifications, identifying their key role in post-transcriptional protein regulation. Integrative analysis of the proteome and m6A methylome identifies a novel regulator in m6A methylation. This comprehensive proteomic and m6A landscape advances our understanding of soybean biology and provides a valuable resource for crop improvement.

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