数字农科院2.0

Transmission of SARS-CoV-2 between ferrets in presence of pre-existing immunity

文献类型： 外文期刊

作者： Chong Wang; Lei Shuai; Gongxun Zhong; Zhiyuan Wen; Renqiang Liu; Qilong Liu; Jinliang Wang; Jinying Ge; Xianfeng Zhang; Yuntao Guan; Xijun He; Zhigao Bu

关键词： SARS-CoV-2; transmission; pre-existing immunity

期刊名称： Journal of Virology

ISSN： 0022-538X

年卷期： 2025 年

页码：

收录情况： SCIE（2025版）

摘要： Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), is characterized by its high contagiousness. The COVID-19 pandemic has exerted profound impacts on human society. The persistent circulation of SARS-CoV-2 in human populations continues to pose re-exposure risks for both vaccinated individuals and those with prior natural infection. Against this epidemiological background, there is an urgent need to characterize the transmission dynamics of SARS-CoV-2 in the context of pre-existing immunity. Using a ferret infection model, this study systematically addresses critical scientific questions, including viral transmission efficiency, temporal patterns of transmissibility, and the ability of pre-existing immunity to mitigate reinfection and viral shedding. The findings provide robust experimental evidence for elucidating the transmission mechanisms of SARS-CoV-2 and offer scientific insights to inform the rational design of optimized antiviral strategies.

分类号：

  • 相关文献

[1]Replication, pathogenicity, and transmission of SARS-CoV-2 in minks. 帅磊,,钟功勋,,温志远,,王翀,,何希君,,刘任强,,王金良,,施建忠,,陈化兰,,步志高. 2021

[2]毛皮动物新冠病毒监测简报. 曹海旭,胡博,张海玲,李双双,李虹晔,赵传芳,廉士珍,刘昊,鲁荣光,白雪. 2020

[3]Replication And Virulence In Pigs O.f The First African S wine Fever Virus Isolated In China. Wang, Xijun,Wu, Xinzhou,Bu, Zhigao,Chen, Weiye,Liu, Xing,Wang, Lulu,Bu, Zhigao,Liu, Renqiang,Wang, Jingfei,Zhang, Jiwen,Zhang, Xianfeng,Zhao, Dongming,Li, Fang,Zhang, Jiaoer,Guan, Yuntao,He, Xijun. 2019

[4]Comparative Genomic Analysis Of The I.id Subtype Family Of C ryptosporidium Parvum. Feng, YY, Li, N, Roellig, DM, Kelley, A, Liu, GY, Amer, S, Tang, K, Zhang, LX, Xiao, LH. 2017

[5]H7N9 Virulent Mutants Detected In C.hickens In China Pose A n Increased Threat To Humans. Shi, JZ, Deng, GH, Kong, HH, Gu, CY, Ma, SJ, Yin, X, Zeng, XY, Cui, PF, Chen, Y, Yang, HL, Wan, XP, Wang, XR, Liu, LL, Chen, PC, Jiang, YP, Liu, JX, Guan, YT, Suzuki, Y, Li, M, Qu, ZY, Guan, LZ, Zang, JK, Gu, WL, Han, SU, Song, YM, Hu, YZ, Wang, Z, Gu, LL, Yang, WY, Liang, LB, Bao, HM, Tian, GB, Li, YB, Qiao, CL, Jiang, L, Li, CJ, Bu, ZG, Chen, HL. 2017

[6]H3N2 Avian Influenza Viruses Detected In Live Poultry Markets In China Bind To Human-Type Receptors And Transmit In Guinea Pigs And Ferrets. Guan, LZ, Shi, JZ, Kong, XT, Ma, SJ, Zhang, YP, Yin, X, He, XJ, Liu, LL, Suzuki, Y, Li, CJ, Deng, GH, Chen, HL. 2019

[7]An insight into the transmission role of insect vectors based on the examination of gene characteristics of African swine fever virus originated from non-blood sucking flies in pig farm environments. 安同庆. 2020

[8]A Single Mutation At Position 1.56 In The Envelope P rotein Of Tembusu Virus Is Responsible For Virus Tissue Tropism And Transmissibility In Ducks. Yan, DW, Shi, Y, Wang, HW, Li, GX, Li, XS, Wang, BB, Su, X, Wang, JH, Teng, QY, Yang, JM, Chen, HJ, Liu, QF, Ma, WJ, Li, ZJ. 2018

[9]Evolutionary Dynamics And Age-Dependent Pathogenesis Of Sub-Genotype Vi.2.1.1.2.2 Ppmv-1 In Pigeons. Xie, P, Chen, LB, Zhang, YF, Lin, QY, Ding, C, Liao, M, Xu, CG, Xiang, B, Ren, T. 2020

[10]Insights Into Insect Vector Transmission and Epidemiology of Plant-Infecting Fijiviruses. Lu Zhang,Nan Wu,Yingdang Ren,Xifeng Wang. 2021

[11]Transmission characteristics of Wheat yellow striate virus by its leafhopper vector Psammotettix alienus. Du, Zhenzhen,Wang, Xifeng,Liu, Yan,Fu, Yumei. 2020

[12]Replication and Transmission of Influenza A Virus in Farmed Mink. Guojun Wang,,Xiaoran Gao,,Guoquan Zhang,,Guohua Deng,,Jianzhong Shi. 2025

[13]A Novel Conserved Linear Neutralizing Epitope on the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein. Rong Hong Hua,Shu Jian Zhang,Bei Niu,Jin Ying Ge,Ting Lan,Zhi Gao Bu. 2023

[14]Rapid and Specific Detection of Active SARS-CoV-2 With CRISPR/Cas12a. Xinyi Liu,Yanhua Li,Xin Wang,Yifan Song,Lina Wu,Benyuan Yu,Xiaodong Ma,Peixiang Ma,Ming Liu,Xingxu Huang,Xinjie Wang. 2022

[15]When RING finger family proteins meet SARS-CoV-2. Cai, Chunmei,Tang, Yan-Dong,Zheng, Chunfu. 2022

[16]An influenza virus vector candidate vaccine stably expressing SARS-CoV-2 receptor-binding domain produces high and long-lasting neutralizing antibodies in mice. Yongzhen Zhao,Lingcai Zhao,Yingfei Li,Qingzheng Liu,Lulu Deng,Yuanlu Lu,Xiaoting Zhang,Shengmin Li,Jinying Ge,Zhigao Bu,Jihui Ping. 2022

[17]Ultrasensitive SARS-CoV-2 diagnosis by CRISPR-based screen-printed carbon electrode. Wu L.,Wang X.,Wu C.,Cao X.,Tang T.,Huang H.,Huang X.. 2022

[18]Heavy Metal, Waste, COVID-19, and Rapid Industrialization in This Modern Era—Fit for Sustainable Future. Adnan M.,Xiao B.,Xiao P.,Zhao P.,Bibi S.. 2022

[19]Gossypol Broadly Inhibits Coronaviruses by Targeting RNA-Dependent RNA Polymerases. Wang, Wenjing,Li, Wenkang,Wen, Zhiyuan,Wang, Chong,Liu, Weilong,Zhang, Yufang,Liu, Juncheng,Ding, Tianze,Shuai, Lei,Zhong, Gongxun,Bu, Zhigao,Qu, Lingbo,Ren, Maozhi,Li, Fuguang. 2022

[20]Large-Scale Functionalized Metasurface-Based SARS-CoV-2 Detection and Quantification. Ahmed, Rajib,Guimaraes, Carlos F.,Wang, Jie,Soto, Fernando,Karim, Asma H.,Zhang, Zhaowei,Reis, Rui L.,Akin, Demir,Paulmurugan, Ramasamy,Demirci, Utkan. 2022

作者其他论文 更多>>