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The Other Side of Defensins: Review of Antiviral Activity of Defensins (Review)

文献类型: 外文期刊

作者: Tao, K.;He, C.;Zhu, Y.;Li, Z.;Shao, D.;Li, B.;Wei, J.;Qiu, Y.;Ma, Z.;Liu, K.

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期刊名称: APPLIED BIOCHEMISTRY AND MICROBIOLOGY

ISSN: 0003-6838

年卷期: 2025 年

页码:

收录情况: SCIE(2025版)

摘要: Defensins are a class of antimicrobial peptides with antiviral, antibacterial, and biomodulatory activities [1, 2]. They present the effector molecules of the innate immune system and play an important role in host defence against pathogens, including enveloped or non-enveloped viruses, fungi and bacteria [3]. Defensins play an important role in virus invasion and infection. Here, we systematically describe the antiviral effects of defensins from four aspects: polypeptide structure, distribution in animals and antiviral mechanisms and applications emphasizing the potential of defensins as antiviral drugs.

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